1157 results
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... and Euglycemic DKA ... for euglycemic DKA ... is closed • SGLT2 ... #Euglycemic #DKA
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
Pathophysiology Euglycemic DKA ... Endocrine #Euglycemic #DKA ... #SGLT2 #Mechanism
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Mechanism #Nephrology #SLGT2
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA ... Ketoacidosis (DKA ... • Euglycemic DKA ... State (HHS) • DKA
Stepwise Approach to Prescription of SGLT2 inhibitors 

Anticipatory Guidance 
• Consider diuretic dose reduction 
Patient Counseling
Prescription of SGLT2 ... • Symptoms Of DKA ... endocrinologists #SGLT2
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... Action: Inhibits SGLT2 ... ketoacidosis (DKA ... #Inhibitors #Pharmacology
Indications for and pharmacological properties of approved SGLT2 inhibitors

Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin

#SGLT2 #Inhibitors
properties of approved SGLT2 ... Ertugliflozin #SGLT2 ... #Inhibitors #pharmacology
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
Ketoacidosis • DKA ... glucose, ask if on SGLT2 ... ketoacidosis in SGLT2 ... inhibitors and SGLT2
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... common trigger for DKA ... 2.6% to 3.2% of DKA ... #DKA #EDKA #Insulin
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2 ... Tablets #Oral #DM2 #Pharmacology