174 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2 ... Tablets #Oral #DM2
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... Action: Inhibits SGLT2 ... mL/minute/1.73 m2 ... EricsMedicalLectures/featured #SGLT2 ... Pharmacology #Summary #DM2
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... kidney), which causes ... /ambcarerx #SGLT2 ... #Medications #DM2
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
-4 inhibitors SGLT2 ... endocrinology #dm2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
agent • Does not cause ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... e.g. diarrhea, nausea ... Pharmacology #Summary #DM2
Terry's Nails

Proximal paleness extending halfway up the nail, often eliminating the lunula. Darker distal band. Seen
cirrhosis, CHF, DM2 ... PhysicalExam #Clinical #Photo
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
relative with DM2 ... associated with DM ... • Secondary Causes ... Management #algorithm #DM2
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... therapy in severe cases ... is closed • SGLT2 ... Kat_Watson #SGLT2
Sebaceous hyperplasia 
 - Yellow papule 
 - Donut-shape 
 - Central umbilication 
 - Telangiectasia
Usually multiple - Causes ... Benign #Clinical #Photo
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Decrease #Diagnosis #DM2