453 results
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Mechanism #Nephrology #SLGT2 ... #Inhibitors #Reabsorption
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... Mechanisms of Action: Inhibits ... mL/minute/1.73 m2 ... #Inhibitors #Pharmacology ... #Summary #DM2 #
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
events TZDs DPP-4 inhibitors ... SGLT2 inhibitors ... endocrinology #dm2
Indications for and pharmacological properties of approved SGLT2 inhibitors

Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin

#SGLT2 #Inhibitors
properties of approved SGLT2 ... inhibitors Canagliflozin ... Ertugliflozin #SGLT2 ... #Inhibitors #pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... /ambcarerx #SGLT2 ... #Inhibitors #Pharmacology ... #Medications #DM2
SGLT2 Inhibitors and Cardiovascular Pathophysiology

#SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i #Inhibitors
Stepwise Approach to Prescription of SGLT2 inhibitors 

Anticipatory Guidance 
• Consider diuretic dose reduction 
Patient Counseling
Prescription of SGLT2 ... inhibitors ... endocrinologists #SGLT2 ... #Inhibitors #Prescription
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
glucose, ask if on SGLT2 ... inhibitor ... ketoacidosis in SGLT2 ... inhibitors and ... SGLT2 deficiency
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... is closed • SGLT2 ... inhibitor should ... Kat_Watson #SGLT2
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
Mechanism of SGLT-2 Inhibitors ... Euglycemic #DKA #SGLT2