22 results
Selective Publication of Antidepressant Trials

A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... Antidepressants #SSRIs ... #Publication #Bias ... #Comparison #FDA
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... IBD Pearls: • IDA ... differentiate IDA ... /other causes
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Reuptake Inhibitors(SNRIs ... Diarrhea, Insomnia, Nausea ... Anorexia, Insomnia, Fatigue ... gain Incr NE: Nausea ... Dry Mouth #SNRIs
Selective Publication of Antidepressant Trials

A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... Antidepressants #SSRIs ... #Publication #Bias ... #Comparison #FDA
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... Idiopathic • Chronic Fatigue ... Syndrome #Chronic #Fatigue ... Diagnosis #Algorithm #causes
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms Anemia ... symptoms related to anemia ... These causes could ... often indicates IDA ... often indicates IDA
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
dermatitis, dementia, anemia ... What doesn't HIV cause ... splenomegaly, cytopenias, nausea ... consumption- number one cause ... splenomegaly, fatigue
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... Presentation: • Fever • Fatigue ... and petechiae Causes
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... Worsening macrocytic anemia ... slowing, neuropathy, fatigue ... wt loss • If anemia ... - CBC, PBS - anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age • 22 and 45 cases ... Symptoms: • Fatigue ... skin that are caused ... Out Secondary Causes