164 results
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
limited by quality/bias ... If 100%, then all ... If 100%, then all ... power) Selection bias ... time Lead-time bias
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Descents, Rales,+S4, MR ... Echocardiography, Cardiac MRI ... : Amyloidosis (AL ... , Danon Disease, ... Diagnosis #Causes #differential
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... There is also fragmentation ... • MRI is more sensitive ... tibial tuberosity Differential ... patella #clinical #mri
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... is from extrahepatic ... Infiltrative - The liver is ... Alcoholic liver disease ... chemistry #diagnosis #differential
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
: - Catch-all term ... lesions may start as ... - Pathophysiology ... is of little guidance ... Targetoid #Algorithm #Differential
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Compatible syndrome + MRI ... lymphoproliferative disease ... lung nodules, may also ... • Metastatic disease ... Lesions #Brain #differential
Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
Complications Vertebral disease ... vertebral canal from all ... spondylitis", which is ... #Spondylosis #pathophysiology
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
MRI shows globular ... low-signal on all ... Differential diagnosis ... tenosynovitis: Differentiate ... #clinical #mri
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • XR, MRI to ... • Differentiate ... Hematogenous spread as ... #differential #
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... Chronic pulmonary diseases ... coronary heart disease ... #Diagnosis #Pathophysiology