1629 results
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
SPEP+free light ... monoclonal gammopathy (SPEP ... hypergammaglobulinemia (SPEP ... expensive than SPEP ... present) - These infections
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
pathways. 6) SPEP ... monoclonal gammopathy (SPEP ... hypergammaglobulinemia (SPEP ... expensive than SPEP ... present) - These infections
Summary of Available Tests for Clostridium difficile Infection, in Decreasing Order of Sensitivity
 • Toxigenic culture
Clostridium difficile Infection ... culture - Sens High, Spec ... tests - Sens High, Spec ... dehydrogenase - Sens High, Spec ... assay - Sens High, Spec
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Sens ~55-96%; Spec ... invasive fungal infection ... surfaces - Infections ... Serum GM: Sens/Spec
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
) • The first step ... Include: • Viral infections ... Protein Gap: • SPEP ... 0.26 - 1.65 SPEP ... size (amount) SPEP
Possible Algorithm for Workup of Fever of Unknown Origin (FUO)
Tier 1 Workup:
 • CBC, comprehensive metabolic
QuantiFERON) • LDH, SPEP ... Qfever), Bartonella spp ... and Brucella spp ... Additional tests for infection
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... #1 nosocomial infection ... immunoassay (↑Spec ... #Clostridium #Infection
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Accuracy Compared - SPEP ... - FLC - UPEP ... Diagnosis #MGRS #MGUS #SPEP
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Sens 55-9536, spec ... surfaces, Albumin, Infections ... Spec 81% for dx
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
Cardiac Aspergillus infection ... • Aspergillus infections ... of eye Infectious