2638 results
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • Viral infections ... gastric tumors • Hematology ... 0.26 - 1.65 SPEP ... size (amount) SPEP ... differential #diagnosis #hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Sens ~55-96%; Spec ... invasive fungal infection ... (IFI) in hematologic ... surfaces - Infections ... Serum GM: Sens/Spec
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Accuracy Compared - SPEP ... - FLC - UPEP ... Diagnosis #MGRS #MGUS #SPEP
Differential diagnosis of Skin + Eye infections
 • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
of Skin + Eye infections ... Bacterial: Staph spp ... spp, Bartonella ... #eye #ocular #dermatology ... InfectiousDiseases #Infections
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Connective Tissue, Infections ... Lymphocytosis: Infection ... Lymphocytopenia: Infections ... • Neutropenia: Infections ... Diagnosis #causes #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... malignancies • Infection ... Algorithm #Causes #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
deficiency) • Infection ... Sepsis • Non-infectious ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... Non malignant hematologic ... states • Non-hematologic ... Algorithm #Causes #Hematology
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
Cardiac Aspergillus infection ... • Aspergillus infections ... of eye Infectious
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections