14 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
#Management #Pediatrics ... #Peds #Febrile ... #Infant #StepByStep ... #Algorithm #LP ... #Antibiotics #Risk
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Infant #StepByStep
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
hemophilia type (e.g ... Avoid meds that ... ↑ bleeding risk ... #Management #treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Prednisone 5mg/kg ... Subacute-Acute: • Common: fever ... #management #hematology
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
patients at highest risk ... Antiparkinsonian agents are diagnostic ... Extreme rigidity, fever ... FDA-approved for TD ... #pharmacology #management
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... indicated • EKG ... Obtain EKG if: ... medical and surgical management ... stratification #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Risk factors 3. ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management