528 results
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
Calcium Channel ... : No effect • Dromotropy ... Chronotropy: Slows • Dromotropy ... CCBs #Calcium #Channel
POCUS - Measuring Cardiac Output
1) Calculate LVOT Area
2) Calculate LVOT VTI
3) Calculate Cardiac Output

SV = (LVOT
Cardiac Output SV ... CO (mL/min) = SV
Mean Arterial Pressure (MAP)

Average arterial pressure throughout one cardiac cycle, systole, and diastole. 
Surrogate indicator of
Stroke Volume (SV ... the chronotropy, dromotropy ... #chronotropy #dromotropy ... cardiacoutput #Co #SV
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Depolarization: • Na+ channels ... Phase • Ca++ channels ... Potential: • K+ channels ... CLASS 1 - Sodium Channel ... Block fast Na+ channels
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
CLASS 1 - Sodium Channel ... Block fast Na+ channels ... 3 - Potassium Channel ... MOA: Block K+ channels ... Block slow Ca++ channels
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
agents - Sodium Channel ... agents - Potassium Channel ... agents - Calcium Channels
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cotransporter, K channel ... , Cl channel, or ... barrtin (recruits Cl channel ... epithelial sodium channels ... epithelial sodium channels
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
to the sodium-channel ... voltage-sensitive calcium channels
Stroke Volume & Cardiac Output Measurement on POCUS
Accurately measure LVOT diameter:
1. Obtain PLAX 
2. Zoom to
LVOT Diam/2) 2 SV
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... Antiarrhythmics #Sodium #Channel