15 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Differentiate ... #Disease #differential ... #diagnosis #causes ... #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
and Causes Increased ... hyperplasia of bone ... #Differential # ... Causes #Workup # ... Hematology #Diagnosis
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
- Differential ... Diagnosis Algorithm ... Vascular #JointPain #MSK ... #Differential # ... #Orthopedics #Causes
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Diagnosis Algorithm ... Tumours - See Bone ... Ricketts - Diffuse Pain ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Chronic Joint Pain ... - Differential ... Diagnosis Algorithm ... Intraarticular #MSK ... #Orthopedics #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... symptoms - Pain ... #hepatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint Pain ... • Ligament • Bone ... the subchondral bone ... #MSK #rheumatology ... approach #workup #differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint pain ... - Aneurysmal bone ... diagnosis #msk #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... Better call hematology ... #Diagnosis #Algorithm ... #workup #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... weeks) Can Be Caused ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular