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diagnosis symptoms differential rheumatology dermatology management causes generalized oncology pruritus ra scleroderma secondary vasculitis workup anorexianervosa arteritis arthritis chronic classification
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening Signs ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... - Systemic and ... renal failure/uremia ... #generalized #dermatology ... Differential #Diagnosis #Algorithm
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... reticularis Blood: Anemia ... interstitial lung disease/pulmonary ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... myopathy • Anti MAG ... thrombosis+Pulm HTN+skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... arthritis, obstructive pulmonary ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... Diagnosis: • Systemic ... Presentation: Systemic ... purpura: Strong sign ... Differential #Diagnosis #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
sx + signs/sx of ... complaints- anemia ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Neutropenia, anemia ... workup #oncology #hematology
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