20 results
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
opsonize pathogen (tag ... #Inflammation #pathophysiology ... #immunology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... #Pharmacology #Pathophysiology ... #immunology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: when any egg ... Neurological Compromise (e.g ... Cardiac Compromise (e.g ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Lipid mediators (e.g ... Other mediators (e.g ... inflammatory mediators (e.g ... #Anaphylaxis #pathophysiology ... #immunology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
phagocytes: Antigen (Ag ... adaptive #immunity #immunology ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cell-dependent Ag ... : Ag-presenting ... storage sites (e.g ... Humoral #Immunity #pathophysiology ... #immunology
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
antagonist use (e.g ... adjunct therapy) e.g ... adjunct therapy) e.g ... Treatments #Management #pathophysiology ... #immunology
COVID-19 Intubation Checklist

Personal protective equipment (PPE)
 • Standard PPE
   • N95 or PAPR.
-19 Intubation Checklist ... dose paralytic (e.g ... at least 1.2 mg/kg ... don't actively bag ... COVID19 #Intubation #Checklist
Emergency Baby Delivery - Equipment Checklist
 • Sterile gloves
 • Sterile scissors
 • 2 Clamps for
Delivery - Equipment Checklist ... absorbable suture (e.g ... - Neonatal bag ... #Delivery #checklist
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology