24 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Retinoblastoma Signs ... partial retinal red reflex ... pathophysiology #ophthalmology ... #diagnosis #signs
Positive Hoffmann's sign (finger flexor reflex)

Flexion and adduction of the thumb and flexion of the index
Positive Hoffmann's sign ... #Hoffmanns #sign ... #clinical #hand ... #orthopedics #neurology ... #sports
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... numbness, decreased reflexes ... Residency @CMC_IM #Potts
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... exertion • Neurologic ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Pathogenesis and Clinical ... - pupillary reflex ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Pathogenesis and Clinical ... elderly, female (short ... bladder, urinary reflux ... Signs/Symptoms ... Pathophysiology #Signs
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
thrombosis of short ... Clinical manifestations ... • Cephalic symptoms ... Doppler US : halo sign ... #Rheumatology #Ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... diffuse light reflex ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings

Predisposing Factors:
 - Immunocompromised, Diabetes,
 - Elderly, Female
Pathogenesis and Clinical ... Elderly, Female (short ... bladder, urinary reflux ... Pathophysiology #Signs ... #Symptoms