33 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... clinical #diagnosis #rheumatology ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #Diagnosis #Management ... #treatment #hematology
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
IV Mg infusion (e.g ... - Tumor lysis syndrome ... High #Magnesium #Table ... #Causes #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
• Serotonin syndrome ... Anticholinergic syndrome ... Sympathomimetic syndrome ... Checklist #Diagnosis #Management ... #Workup
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
Pancreatitis management ... guide etiology & management ... abdominal compartment syndrome ... limit them as able ... Checklist #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... with previously stable ... White-coat syndrome ... Guillain-Barre Syndrome ... #Hypertension #Workup
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... SPS #Diagnosis #Management