39 results
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
activation 3- DC ... phagocytes: Antigen (Ag ... adaptive #immunity #immunology ... #pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
IL-2 Muromonab-CD3 ... #Pharmacology #Pathophysiology ... #immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
opsonize pathogen (tag ... #Inflammation #pathophysiology ... #immunology
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology ... #inflammatory #immunology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
-> Particular CD4 ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Perforation) Pathophysiology ... • Flex-Sig: If ... IDSA 2021 CDI ... management #treatment #infectiousdiseases
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cell-dependent Ag ... : Ag-presenting ... to CD4+ helper ... Humoral #Immunity #pathophysiology ... #immunology