21 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Ketoacidosis (DKA ... Polydipsia #dka ... #hhs #pathophysiology ... #comparison #endocrinology
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology ... and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA ... #Endocrinology
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... look like overlap DKA ... BrighamChiefs #DKA ... laboratory #diagnosis #endocrinology
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA ... #Pathophysiology ... #Endocrinology
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
Ketoacidosis (DKA ... • Euglycemic DKA ... Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... diagnosis #management #endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... 2.6% to 3.2% of DKA ... Common, early signs ... #DKA #EDKA #Insulin
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... In DKA, the normal ... #Ketoacidosis #DKA ... #Diabetes #Endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
ketoacidosis (DKA ... • Euglycemic DKA ... • DKA/HHS Overlap ... features of both DKA ... diagnosis #management #endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs ... /DKA: Both: Polyuria ... , hypotension) DKA ... #EM #IM #Endo #DKA
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Treating DKA: 1) ... DiabeticKetoacidosis #DKA ... #endocrinology