12 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... result from low blood ... #management
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss ... Deficiency • Aplastic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Vascular Skin Lesions - Differential Diagnosis Algorithm
 - Petechiae < 0.2 cm diameter
 - Purpura 0.2
Vascular Skin Lesions ... dilated superficial blood ... discolorations of skin ... Vascular #Vasculitis #SkinRash ... #dermatology #Differential
Pustular Skin Rash - Differential Diagnosis Algorithm
Pruritic / Scaly / Erythematous lesions, usually poorly demarcated
Acneiform -
Pustular Skin Rash ... Differential Diagnosis Algorithm ... body folds with satellite ... #Pustular #SkinRash ... #dermatology #Differential
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... Differential Diagnosis Algorithm ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... / Systemic == Blood ... renal failure/uremia ... #generalized #dermatology ... Differential #Diagnosis #Algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... just beneath the skin ... • Aplastic Anemia ... Megaloblastic Anemia ... Syndromes #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Differential Diagnosis Algorithm ... Blood Glucose ... renal failure/uremia ... #generalized #dermatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... due to marrow aplasia ... infections with skin ... Transfusions #diagnosis #management ... #hematology #reactions