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diagnosis hematology oncology algorithm differential generalized mds myelodysplastic pruritus secondary systemic treatment atopic atopy cll dermatitis eczema lymphocytic medications myelodysplasia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... and petechiae Causes ... #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Creatinine & BUN: • Chronic ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... • Neutropenia, anemia ... Pure red cell aplasia ... #CLL #Chronic
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... • Anemia • Aplastic ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... Dermatitis (AD) is a chronic ... #management #medications ... treatment #diagnosis #causes ... #skinrash References
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