14 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
molecular weight heparin ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... and bridging for VTE ... Clotmaster #VTE ... #DOAC #Bridging ... #Pharmacology #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... low-molecular-weight heparin ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... not available #DOAC ... #Oral #anticoagulant ... #hematology #management
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... from Warfarin to DOAC ... #pharmacology #management ... #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
, CF, IBD) • Anticoagulant ... Medications - Heparin ... LMWH, warfarin, DOACs ... comparison #diagnosis #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... arterial thrombosis, skin ... exposure (prevent skin ... , Bivalirudin, DOAC ... #Treatment #Hematology
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... assay; ECT = ecarin ... thrombin time #doac ... #noac #anticoagulation ... #hematology #laboratory