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hematology oncology differential leukemia chronic cll hemeonc rheumatology syndrome classification common comparison cvid eosinophilia eosinophils hemophagocytic hes hlh hodgkins hypereosinophilia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... #hemeonc #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... lymphoproliferative disorders ... • Neutropenia, anemia ... #Leukemia #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... leakage of RBC's secondary ... - Hemolytic anemia ... #nonpalpable #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... biopsy demonstrates lymphocytes ... Systemic Fibrosis: - Secondary ... #Differential #Diagnosis ... comparison #table #dermatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) - Diagnosis ... and Management ... blood eosinophilia Secondary ... Myeloproliferative HES - Lymphocytic ... #hematology #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... lymph node biopsy (diagnostic ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... DDX: Rule Out Secondary ... Neutropenia • Platelet Disorders ... Myelodysplastic #Syndromes #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... other diseases • Secondary ... UIP, NSIP): • Lymphocytic ... lubricants • Pharmacologic ... #Management
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