10 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... , Rivaroxaban, Apixaban ... DOAC, Parenteral anticoagulant ... anticoagulation #Switching #hematology ... #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Dosing #Oral #Anticoagulant ... Anticoagulation #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Rivaroxaban • Apixaban ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #Direct #Oral #AntiCoagulant
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... (Praxbind) - Apixaban ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
procedure Stop anticoagulant ... Antidotes: • Apixaban ... Reversal #NOAC #Oral #anticoagulant ... #hematology #management ... #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
clot #PT #PTT #diagnosis ... #models #hematology ... anticoagulation #anticoagulant ... thrombin #inhibitor #Apixaban
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... DIC, TTP/HUS • Anticoagulants ... #Differential #Diagnosis ... #hematology #rheumatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... heparin - Other anticoagulants ... Prolonged #Causes #diagnosis ... #differential #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... cold IgG • Lupus anticoagulant ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
history, e.g. anticoagulants ... membrane bleeding and skin ... peds #pediatrics #diagnosis ... #hematology #primarycare