4 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT # ... Pharmacology #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... Reversal #NOAC #Oral ... anticoagulant #hematology ... #management #pharmacology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... just beneath the skin ... cell types are abnormal ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology