7 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common Reversal ... PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
Very Quick Guide to Reversing Antithrombotic Therapy
Aspirin 
Clopidogrel 
Prasugrel 
Ticagrelor 
Abciximab 
Tirofiban 
Eptifibatide 
Unfractionated Heparin 
Low
Unfractionated Heparin ... Molecular Weight Heparin ... Dabigatran Apixaban ... Anticoagulation #Reversal ... Antiplatelet #Management #Hematology
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy
Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Unfractionated Heparin ... Molecular Weight Heparin ... Bivalirudin, Dabigatran, Apixaban ... DeLoughery @Bloodman #Reversal ... anticoagulation #agents #hematology
Standard Heparin Reversal: Protamine
  < 30 minutes - 1 unit/100 units of heparin
  30-60
Standard Heparin ... Reversal: Protamine ... #Reversal #Protamine ... #pharmacology # ... management #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... Antidotes: • Apixaban ... available #DOAC #Reversal ... anticoagulant #hematology ... #management #pharmacology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... arterial thrombosis, skin ... including flushes), reverse ... exposure (prevent skin ... Management #Treatment #Hematology