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diagnosis hematology leukemia myelodysplastic anemia aplastic clinical cll cutaneous differential erythematosus lupus lymphocytic management manifestations myelodysplasia sle syndromes systemic workup
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... differential #diagnosis #dermatology ... #oncology #clinical ... #skin
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... just beneath the skin ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... (C3 and C4) • ds-DNA ... with Lupus: • Chronic
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