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diagnosis management latenttb tb tuberculosis acromegaly differential endocrinology hematology hemeonc hemophagocytic hlh immune inflammatory iris lymphohistiocytosis muscle myopathy neurology person
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Pathophysiology ... Clinical Manifestations ... continuous motor unit activity ... Continuous motor-unit activity ... Treatment: •
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... • Tuberculin skin ... Tuberculosis Treatment ... Initiating Treatment
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... weakness without skin ... any time during treatment ... IU/I • SAMS clinical ... increased spontaneous activity
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... • Tuberculin skin ... Tuberculosis Treatment ... Initiating Treatment
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... , hair growth, skin ... Beckwith Wiedemann syndrome ... Endocrinology #Treatment ... #Pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... nodes: 13-15%, skin ... • Heerfordt syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... salivary ducts Clinical ... amyloidosis, PAH Skin ... Adenocarcinoma Treatment ... muscarinic agonists • Active
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... cavitating pneumonia, skin ... • Persistently active
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... hyperinflammatory syndrome ... Clinical Presentation ... Pathophysiology ... absent NK-cell activity
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