7 results
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... - Pathophysiology ... UCSD Internal Medicine ... #Pathophysiology ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
, hair growth, skin ... tags, skin thickening ... malignancy Pathophysiology ... occurs secondary ... Diagnosis #Management #Endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Congenital Adrenal ... Early puberty, Secondary ... gonadal failure • Skin ... resistance • Adrenal ... Symptoms #diagnosis #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... as "congenital adrenal ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly ... Renal parenchymal ... Jcortesizaguirr #Secondary
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
• Acne • If secondary ... menstrual cycles 5) Secondary ... the abdomen for adrenal ... tumors • The adrenal ... signs #symptoms #endocrinology