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diagnosis gh growthhormone signs 21hydroxylasedeficiency 21ohd cushings excess feedbackloop genetics hypercortisolism management pediatrics peds pituitary syndrome treatment
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... hemianopsia IGF-1 Overproduction ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... - Giantism or acromegaly ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
, hair growth, skin ... tags, skin thickening ... malignancy Pathophysiology ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Clinical Features 1) Skin ... easily bruisable skin ... due to an overproduction ... Diagnosis #signs #symptoms ... #endocrinology
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