12 results
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... UCSD Internal Medicine ... Insufficiency #Pathophysiology ... #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
synthesis in the skin ... #Pathophysiology ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
, hair growth, skin ... tags, skin thickening ... malignancy Pathophysiology ... #Endocrinology ... #Treatment #Pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... arterial thrombosis, skin ... ♀, ↑Age, ESRD Pathophysiology ... Management: • ... exposure (prevent skin
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... integrity of: • Skin ... Muscle cramping Skin ... #AscorbicAcid #Pathophysiology ... Nutrition #Diagnosis #Management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... nodes: 13-15%, skin ... Sarcoidosis #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... • Tuberculin skin ... TB #Diagnosis #Management