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diagnosis dermatology differential rheumatology vasculitis addisons adrenal antimda5 antimda5dm antinxp2 antinxp2dm classification clinical disease disorders distribution endocrinology eosinophil eosinophilia hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Causes: • Autoimmune ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... eosinophilia (common ... causes are asthma ... organ-specific signs ... symptoms (eg, skin
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Internal organs Most common ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... commonly characterize ... The signs and symptoms ... resembling rashes caused
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... #causes
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Common Dermatological ... associated with signs ... macerated areas with satellite ... #dermatology #rash ... #common #distribution
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Drug Associated (Commonly ... Associated: (± 100 % Commonly ... mucositis - Rash ... purpura: strong sign
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Inflammatory Myopathies: Commonly ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign
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