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diagnosis differential hematology symptoms vasculitis antinxp2 antinxp2dm chronic classification cll dermatology dermatomyositis downs erythematosus features hemophagocytic hlh leukemia lupus lymphocytic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... response to local skin ... syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
Characteristic clinical ... folds (a fold of skin ... anomalies • Short neck ... #Downs #Syndrome ... PhysicalExam #Features #Signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet ... Syndrome: - Recurrent ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... vasculitis • Behcet ... syndrome: Recurrent ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... cells can indicate disease ... • Richter’s Syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... chest (in a V-sign ... shoulders (in a shawl sign ... had more severe disease ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... • Inner ear • Skin ... Sarcoidosis • Behcet ... Polychondritis #rheumatology ... #diagnosis #management
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