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diagnosis differential comparison dermatology hematology leukemia management oncology table vasculitis antimda5dm autoimmune behcet classification cll cold dermatomyositis fungal infections infectiousdiseases
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... Hepatomegaly • Skin ... cells can indicate disease ... leukemia #CLL #Chronic
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
trigger - Direct skin ... infiltration (lymphocytes ... , Chronic spontaneous ... urticaria, Chronic ... Urticaria #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... extramedullary disease ... CLL -> Invade Skin ... #Leukemia #Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... severity of the disease ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology #
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
biopsy demonstrates lymphocytes ... patients with kidney disease ... large numbers of stellate ... frequent in men Chronic ... Graft-Versus-Host Disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... test (this is a skin ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... elevated protein, lymphocytic ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... Eosinophilia, asthma, chronic ... - Affects the skin ... purpura: strong sign ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... muscular atrophy • Chronic
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... osteomyelitis or skin ... count (mainly lymphocytes ... organism into the skin ... Mouth, throat, skin
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