13 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... Hepatomegaly • Skin ... cells can indicate disease ... #Lymphocytic #Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... Lymphocytic Leukemia ... CLL -> Invade Skin ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... #Lymphocytic #Leukemia ... #hemeonc #diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
infiltration (lymphocytes ... , Chronic spontaneous ... urticaria, Chronic ... Cold #Urticaria #diagnosis ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
severity of the disease ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... tears, Ischemia, Leukemia ... Recurrent and chronic ... #management #signs ... #symptoms #rheumatology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... biopsy demonstrates lymphocytes ... patients with kidney disease ... frequent in men Chronic ... Graft-Versus-Host Disease
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... elevated protein, lymphocytic ... Eosinophilia, asthma, chronic ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Eosinophilia, asthma, chronic ... Differential Diagnosis ... purpura: strong sign ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... #Rheumatology