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diagnosis differential erythematosus infections infectiousdiseases lupus management sle systemic vasculitis antimda5dm autoimmune behcet classification dermatology dermatomyositis fungal hiv mycoses myopathy
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... anti-NXP2 Abs Lung ... • Arthralgia/arthritis ... #AntiMDA5 #Dermatomyositis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... meningitis), MCC CNS symptoms ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... effusion, Restrictive lung ... of hip (rare), Arthritis ... erythematosus #signs ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
- Signs and Symptoms ... Pulmonary: Parenchymal lung ... of DMARDs • Skin ... #RA #Signs #Symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms ... with Lupus: • Chronic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... and often causes arthritis ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Diagnosis Framework Disease ... • CT: Halo sign ... Constitutional symptoms ... Abdominal pain, chronic ... Infections #HIV #AIDS
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... • Nonerosive arthritis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... yeast • At risk: AIDS ... change in the lungs ... Meningitis, septic arthritis ... nails, bronchi, lungs
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