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symptoms differential management sjogrens syndrome systemic addisons adrenal antinxp2 cryofibrinogenemia dermatology dermatomyositis disease endocrinology erythematosus hematology insufficiency lupus myopathy myositis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... thickening Signs ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... erythematosus (SLE) Signs ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... Serum DHEAS Diagnosis ... patches on the skin ... endocrinology #diagnosis ... #signs #symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... associated with autoimmune ... Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia #diagnosis ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Lacrimal swelling • Skin ... Vaginal dryness • Primary ... hepatitis, primary ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... rheumatologic diseases ... the context of primary ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... three days #AntiNXP2DM ... #diagnosis #management ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
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