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diagnosis differential systemic addisons erythematosus insufficiency lupus management sle vasculitis antinxp2 arthritis classification dermatology dermatomyositis disease endocrinology myopathy myositis polychondritis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
- Vitiligo - Autoimmune ... nervous system symptoms ... disorders: - Pale skin ... Insufficiency #Signs ... #Symptoms #Adrenal
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... pseudomonas) Autoimmune ... develop another autoimmune ... Reduced libido • Signs ... patches on the skin
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Abdominal pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... Presentation - Systemic Symptoms ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Complications of DMARDs • Skin ... Pericarditis • Renal ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... Induced Lupus: • Symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... • Clear cell renal ... three days #AntiNXP2DM ... diagnosis #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
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