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differential symptoms dermatology management dermatomyositis hematology systemic vasculitis workup algorithm antimda5 antimda5dm antinxp2 arteritis arthritis autoimmune behcet chronic classification cll
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
LcSSc) - distal skin ... thickening Signs ... changes): skin ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #management #signs ... #symptoms #rheumatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... on sun-damaged skin ... macerated areas with satellite ... #differential #diagnosis ... #skin #common #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Differential Diagnosis ... purpura: strong sign ... #differential #diagnosis ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... three days #AntiNXP2DM ... #diagnosis #management ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs
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