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diagnosis vasculitis behcet classification clinical cutaneous dermatology disease erythematosus gap globulin hematology inflammatory lupus management manifestations myelodysplastic myopathies myopathy myositis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... Autoimmune manifestations ... #differential # ... oncology #clinical #skin
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... test (this is a skin ... Behcet disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... • Cogan Syndrome ... ear disease Differential ... purpura: strong sign ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... purpura: Strong sign ... #Vasculitis #Differential ... #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... Cirrhosis, ETOH, autoimmune ... Gap #ProteinGap #differential ... #diagnosis #hematology
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