5 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis (Scleroderma ... Multi-system autoimmune ... thickening Signs ... #SSc #rheumatology ... #diagnosis #signs
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Scleroderma Like ... reduced incidence Scleredema ... large numbers of stellate ... - Can produce scleroderma-like ... Differential #Diagnosis #comparison
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Autoimmune diseases ... trigger - Direct skin ... 50% of patients Skin ... Urticaria #diagnosis #rheumatology ... #comparison #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... differential #diagnosis #comparison ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology