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diagnosis antidrugantibodies antitnffailure b12 checkpointinhibitor cobalamin colitis deficiency druglevels immune nutrition resistance vitamin
Algorithm for managing the failure of anti-TNF therapy. ADA=anti-drug antibody; IM=immunomodulator; MOA=mechanism of action; TNF=tumor necrosis
Algorithm for managing ... anti-drug antibody; IM ... necrosis factor #Management ... #GI #IM #IBD #AntiTNFFailure ... #BMJ
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
diarrhea related to IBD ... total body stores Evaluation ... previously dx'd associated ... , can consider IM ... Deficiency #diagnosis #management
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
: Increase < 4 BMs ... indicated Diagnostic Evaluation ... -4 • Consult GI ... Colitis #diagnosis #management ... #algorithm #IBD
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