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diagnosis hematology differential causes management mds myelodysplastic abnormal abnormalities agglutinin algorithm aplastic breathing cryofibrinogenemia disease dyspnea hemolytic leukemia monoclonal myelodysplasia
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Diseases Nail Fold ... Iron deficiency anemia ... • Nephrotic syndrome ... #dermatology #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Syndrome (CAS): ... • Symptoms of anemia ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... diagnosis: 70 years old ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #oncology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... - Asthma - COPD ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia •
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Anticonvulsants - Gold ... marrow-failure syndromes ... #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... #rheumatology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Oncology #Diagnosis
Abnormalities in Rate and Rhythm of Breathing Normal The respiratory rate is about 14—20 per min
breathing may be secondary ... heart failure, uremia ... hyperventilation syndrome—a ... bronchitis, and COPD ... Breathing #Patterns #Pulmonary
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