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diagnosis management oncology hemeonc leukemia cll heparin hit induced lymphocytic 4ts 4tscore algorithm cell common comparison criteria cvid druginduced hemophagocytic
Approach to suspected Heparin-Induced Thrombocytopenia (HIT) • Suspected HIT Algorithm • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... Algorithm • "4 T's" clinical ... probability score ... : - Thrombocytopenia ... #HIT #hematology
4T Score for Heparin-Induced Thrombocytopenia Interpretation of the 4T score: 0-3 points: Low probability (<<1%) -
4T Score for Heparin-Induced ... Thrombocytopenia ... Interpretation of the 4T score ... - No further workup ... Diagnosis #Criteria #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis: • Clinical ... → Calculate 4T score ... • If 4T score ... non-heparin A/C if clinical ... Management #Treatment #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... with anemia or thrombocytopenia ... uw_IMresidency #CLL #Chronic ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... Neutropenia, anemia, thrombocytopenia ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... activity • ↓ LAP Score ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... specifically immune thrombocytopenia ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... • Evolution: Chronic ... comparison #table #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... Marrow Failure • Chronic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... Clinical Presentation ... Cytopenias (anemia, thrombocytopenia ... molecular diagnosis: HScore ... Diagnosis #Management #Hematology
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