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differential dermatology rheumatology sle algorithm alopecia causes classification erythematosus hairloss joint oncology pain systemic table clinical compared conditions cryoglobulinemia cryoglobulins
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... lesions • Discoid lupus ... #differential #diagnosis
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... - Differential Diagnosis ... soles • Discoid Lupus ... Papulosquamous #SkinRash ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... Differential Diagnosis ... such as systemic lupus ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... erythematosus (SCLE ... Differential Diagnosis ... Seizures • Strokes Skin ... Erythematosus #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... signs #symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... New headache, scalp ... #Differential #Diagnosis ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... • Autoimmune diseases ... reticularis & skin ... Labs/Diagnosis: ... (e.g. systemic lupus
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... Alopecia totalis (all scalp ... - Secondary to Skin ... Disease • ... #Differential #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
is rare in DIL, SCLE-DIL ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Eruptions (Face/Scalp ... Inflammatory, pus-filled sore ... #Differential #Diagnosis ... #Dermatology
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