12 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver cirrhosis ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulopathy, cirrhosis ... antiphospholipid syndrome ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... - Differential Diagnosis ... - Oncotic • Cirrhosis ... • Asbestos • Uremia ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... and Primary Causes ... renal failure/uremia ... Myelodisplastic syndrome ... #Algorithm #causes
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
- Differential Diagnosis ... Pulse Pressure = Systolic ... iron deficiency anemia ... - Obesity - Cirrhosis ... Acute Coronary Syndrome
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
Causes of Anemia ... in Cirrhosis - ... Differential Diagnosis ... Destruction: Zieve's syndrome ... #Diagnosis #Hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Central nervous system ... primary biliary cirrhosis ... Nephrogenic DI Hematologic
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
air conditioning system ... Bandemia, AKI. ... dogs & latter can cause ... asplenia, alcoholism, cirrhosis ... the key to the diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology ... #Algorithm #causes