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management differential diuresis diuretics excretion gitelman hyponatremia hypotonic leukostasis lysis medications pharmacology physiologic tls tumor
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... #diagnosis #nephrology ... #Hypokalemia
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... , Hypervolemia with ... #differential #diagnosis ... #table #sodium ... #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... hydration - Hyperkalemia ... #TLS #diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Metabolic alkalosis ... • Diagnosis of ... Kidney stones caused ... Tolvaptan) • Treatment ... #Medications #Table
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