10 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... syndrome - Mutation ... • Bartter syndrome ... #nephrology #management ... #pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Syndrome, Gitelman ... Syndrome Volume ... GRA, Cushing's syndrome ... , Liddle syndrome
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... - Urinary Chloride ... use, Bartter syndrome ... , Gitelman syndrome ... #Urinary #Chloride
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... , Bartter's syndrome ... use), Gitelman's ... syndrome (mimics ... excess and related syndromes
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... Severe Cushing syndrome ... Congenital AME syndrome ... syndrome (defective ... calcium) alkali syndrome
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... ↓ Aldosterone: Syndrome ... excess, Liddle's syndrome ... syndrome, Gitelman ... syndrome -
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypokalemia - Hypomagnesemia ... - Metabolic Alkalosis ... #Syndrome #Diagnosis ... #Workup #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Syndrome, Gitelman ... Syndrome Euvolemic ... GRA, Cushing's syndrome ... , Liddle syndrome
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... and metabolic alkalosis ... Hypercalcemia, Cushing's syndrome ... White-coat syndrome ... Guillain-Barre Syndrome
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome ... #Diuresis #Nephrology