29 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... vomiting) • Low K ... Diagnosis #Algorithm #nephrology ... #low #potassium
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... transcellular shifts ... with impaired renal ... function, medication ... and underlying renal
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... loss • Renal ... Renal tubular acidosis ... #nephrology #potassium
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... (if preserved renal ... #management #potassium ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... loss • Medication ... Transcellular shift ... Diagnosis #Algorithm #Causes ... #Classification
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Hyperkalemia Management ... • Treat the cause ... and parenteral potassium ... Intracellular K+ ... Shift 3) K+ Excretion
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal ... causes • Laxative ... #nephrology #low