27 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... Transcellular shift ... Gittelman's syndrome • Magnesium ... • Renal artery ... #Nephrology #Differential
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
intake, Gl loss, shift ... cells FEMg >4% = renal ... if renal function ... differential #diagnosis #causes ... #nephrology #magnesium
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... - Shift from extracellular ... - Insulin (high ... differential #diagnosis #nephrology ... #Causes #hypomg
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
by Mechanism Renal ... intake - Magnesium ... Differential #Diagnosis #High ... #Magnesium #Table ... #Causes #Management
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Causes of Hypomagnesemia ... with secondary, hypocalcemia ... hypomagnesemia Renal ... #nephrology #magnesium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
K; also binds magnesium ... nonspecifically binds K, magnesium ... patients sensitive to high ... #medications #pharmacology ... #table #comparison
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Intracellular Shift ... Renal artery stenosis ... Algorithm #Diagnosis #Causes ... #Workup #Nephrology
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
Transcellular Shift ... Alkalosis • Hypokalemia ... Increased Excretion - Renal ... : • Aluminum/Magnesium ... endocrinology #causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
potassium(K) & magnesium ... suggests extra-renal ... causes • Laxative ... urinary losses: • High ... differential #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high ... #nephrology