11 results
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... #urine #potassium ... #differential # ... algorithm #diagnosis
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #differential # ... diagnosis #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... • Diarrhea A urine ... urinary losses: • High ... #diagnosis #Algorithm ... #differential #
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... #potassium #high
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
- Differential ... Diagnosis Algorithm ... isolation) GI loss - Urine ... Transcellular shift ... #Diagnosis #Algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Weakness - Dark urine ... Shift of extracellular ... Monitor potassium
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Shift of extracellular ... hour with goal urine ... Monitor potassium ... Dialysis for severe hyperkalemia
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
- Differential ... Diagnosis Framework ... • Cellular Shift ... #Differential # ... #potassium #high
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic ... algorithm for hypokalemia ... Na/Cl < 0.7, high ... correcting serum potassium ... #diagnosis #differential