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differential injury management aflp drug druginduced fatty gastroenterology hepatitis idiosyncratic induced liverenzymes malignant obgyn obstetrics pathophysiology pregnancy
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... for alternative causes ... disorder (e.g. ascites ... #Algorithm #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... Algorithm Portal ... disease • Acute liver ... #Algorithm #Hepatology ... #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... develops (DIC, ascites ... 10x ULN), ↑Tbili/Dbili ... ) Differential Diagnosis ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... #differential #diagnosis ... #algorithm #hepatology
Common Malignancies That Cause Ascites The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
Malignancies That Cause ... - Most common cause ... most frequent cause ... #Differential #Diagnosis ... #Hepatology #oncology
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