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diagnosis hepatology liver differential gastroenterology acute chemistry drug failure idiosyncratic induced injury interpretation transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Liver Injury (DILI ... ) Viral Hepatitis ... #Acute #Chronic
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... - ongoing ↑ LFTs ... Calculate R-Value ... gastroenterology #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Liver Failure (ALF ... : < 1 • Cirrhosis ... transaminitis #LFTs ... #RValue #interpretation
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